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SAR405 R enantiomer

🥰Excellent
Catalog No. T12831Cas No. 1946010-79-2

SAR405 (R enantiomer) is the less active form of SAR405, an inhibitor of PIK3C3/Vps34.

SAR405 R enantiomer
Other Forms of SAR405 R enantiomer:
SAR405T12831L1523406-39-4
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SAR405 R enantiomer

🥰Excellent
Purity: 98.04%
Catalog No. T12831Cas No. 1946010-79-2
SAR405 (R enantiomer) is the less active form of SAR405, an inhibitor of PIK3C3/Vps34.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$40In StockIn Stock
5 mg$93In StockIn Stock
10 mg$161In StockIn Stock
25 mg$275In StockIn Stock
50 mg$398In StockIn Stock
100 mg$557In StockIn Stock
200 mg$759In StockIn Stock
1 mL x 10 mM (in DMSO)$91In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:98.04%
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COA LCMS HNMR HPLC

Product Introduction

Bioactivity
Description
SAR405 (R enantiomer) is the less active form of SAR405, an inhibitor of PIK3C3/Vps34.
Chemical Properties
Molecular Weight443.85
FormulaC19H21ClF3N5O2
Cas No.1946010-79-2
SmilesC[C@@H]1COCCN1c1cc(=O)n2CC[C@@H](N(Cc3cncc(Cl)c3)c2n1)C(F)(F)F
Relative Density.1.51 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (225.30 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (9.01 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2530 mL11.2651 mL22.5301 mL112.6507 mL
5 mM0.4506 mL2.2530 mL4.5060 mL22.5301 mL
10 mM0.2253 mL1.1265 mL2.2530 mL11.2651 mL
20 mM0.1127 mL0.5633 mL1.1265 mL5.6325 mL
50 mM0.0451 mL0.2253 mL0.4506 mL2.2530 mL
100 mM0.0225 mL0.1127 mL0.2253 mL1.1265 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

SAR-405 R enantiomerSAR405 R enantiomerPIK3C3/Vps34.Inhibitorinhibit
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